Method Development and Determination of Levodopa in Pharmaceutical Dosage Forms by Visible Spectrophotometry
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 12
Abstract
Two simple, accurate and economic spectrophotometric methods A and B have been developed for the determination of levodopa in bulk and dosage forms. These methods are based on the formation of chloroform soluble ion-associates in the presence of acidic dyes namely Bromo Phenol Blue, BPB (Method A) and Bromo Cresol Purple, BCP (Method B) exhibiting max at 418 nm each. These methods obey Beer’s law in the concentration range of 2.0-10.0 μg/mL for both the methods. The molar absorptivities are found to be 8.77x103 and 1.94x104 L/mol.cm for methods A and B respectively. These methods are found to be suitable for the assay of levodopa in pharmaceutical formulations.
Authors and Affiliations
Dr. Rambabu C
Keywords
Related Articles
- EP ID EP205099
- DOI -
- Views 82
- Downloads 0
HPTLC finger printing profile of flower extract of Punica granatum
The main objective of the study is to investigate the fingerprint profile of Punic granatum using high performance thin layer chromatography (HPTLC) technique. Camag HPTLC system equipped with TLC Linomat V applicator, C...
Demography of Rabies in India
Rabies is reported endemic worldwide. Approximately 30 000 deaths in India were reported due to rabies especially, 1 between 30% and 50% of these deaths occurred in children in 1998. Rabies has been a disease of antiquit...
Removal of Mordant Green 17 and Acid Fast Red from Water using Nanokaolin
Increasing concentrations of dyes including mordant green17 and acid fast RN in surface and groundwater are a major environmental concern in recent years. In this research, the potential of nanokaolin for efficient remov...
Dystonia: A systemic review
Dystonia is a development issue in which muscles contract automatically, causing dull or bending developments. The condition can influence one a player in your body (focal dystonia), at least two adjoining parts(segmenta...
The Attenuation Effects of Apigenin, Vitexin, Hyperoside and Quercetin on Carrageenan-Induced Mice Tail Thrombosis Model
Flavonoids exert different pharmacological actions, such as analgesic, anti-inflammatory and cardioprotective activities Apigenin, vitexin, quercetin and hyperoside are flavonoids found within medicinal plants. We aimed...