Molecular regulatory mechanism of Krüppel-like factor 9 in tumor development
Journal Title: Chinese Journal of Clinical Research - Year 2025, Vol 38, Issue 5
Abstract
Krüppel.like factor 9 (KLF9) is a transcription factor containing three Cys2His2 zinc finger structures with a wide range of biological functions, including regulation of embryonic development, cell proliferation, apoptosis, differentiation, metastasis and invasion. This article discusses the biological features, expression in different tumors and regulatory mechanisms of KLF9, and the prospects for its future applications.
Authors and Affiliations
LIU Cunyu, KONG Xia, WANG Shiqi, HE Zhiwei
Keywords
Related Articles
- EP ID EP767670
- DOI 10.13429/j.cnki.cjcr.2025.05.028
- Views 15
- Downloads 0
Advances in diagnosis and treatment for diabetic foot
Diabetic foot is often accompanied by vascular and neural damage, infections, and inflammation, which interact to hinder wound healing. The current treatment methods include debridement, infection control, vascular repai...
Best evidence summary for the prevention and management of postoperative delirium in patients with Stanford type A aortic dissection
Objective To retrieve, evaluate, and integrate the best evidence related to the prevention and management of postoperative delirium in patients with Stanford type A aortic dissection at home and abroad. Methods Referring...
Incidence and risk factors of calf muscular venous thrombosis in patients with severe acute ischemic stroke in NICU
"<b>Objective</b> To investigate the incidence of calf muscular venous thrombosis (CMVT) and analyze its risk factors among patients with severe acute ischemic stroke (AIS) in the Neurological Intensive Care Unit (NICU)...
Circulating tumor cell with neutrophil to lymphocyte ratio in predicting efficacy of advanced gastric cancer
<b>Objective</b> To investigate the predictive effect of circulating tumor cell (CTC) combined with neutrophil to lymphocyte ratio (NLR) on efficacy of advanced gastric cancer. <b>Methods</b> The clinicopathological data...
Relationship between polyamines and polyamine metabolism with malignant tumors
Polyamines such as spermine, spermidine, and putrescine play pivotal roles in the proliferation, differentiation, and development of eukaryotes. Multiple regulatory mechanisms strictly control intracellular polyamine con...