Antioxidant And Cytotoxic Activities Of Crude Methanolic Extract Of Medicago Polymorpha
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2013, Vol 3, Issue 8
Abstract
Free radicals are the source of many diseases such as diabetes mellitus, cancer, arthritis, anemea, Parkinson disease, alzimer and ageing etc. Antioxidants are very important for treatment of this disease by scavenging free radicals. The present study was conducted to determine the Cytotoxic and antioxidant activities of metanolic extract of Medicago polymorpha against free radicals such as DPPH and ABTS etc in vitro. These activities of Medicago polymorpha are count for its anticancer properties. The results were analyzed by the comparison of the extract with the standards. Ascorbic acid was used as a standard for antioxidants assays and see salt solution without extract was used a standard for cytotoxic assays. The antioxidant property may be related to the polyphenols and flavonoids present in the extract. These results clearly indicate that Medicago polymorpha is effective against free radical mediated disease and thus it has potential for treating cancer.
Authors and Affiliations
Muhammad Khan, Syed Waqas, Suhaib Asad
Keywords
Related Articles
- EP ID EP109761
- DOI -
- Views 147
- Downloads 0
Phytochemical Screening and In-vitro Antibacterial Activity of Mangifera indica (Mango) Kernel on Aeromonas caviae
[b] OBJECTIVE: [/b] To determine the phytoconstituents of Mangifera indica kernel and its antibacterial activity against Aeromonas caviae. [b]METHODS: [/b]Methanol extract of mango kernel was used to identi...
[b]CONTRACT RESEARCH ORGANIZATION AND ITS GROWTH CRITERIA[/b]
Antifungal activity of Hyptis spicigera (Lamiaceae) extracts and essential oils of Cymbopogon citratus (Poaceae) and Cymbopogon giganteus against the growth of Aspergillus strains isolated in Burkina Faso
Abstract: Antifungal activity of local plant extracts on the growth of seven reference and local isolated strains of Aspergillus was tested. The extracts were composed of essential oils (E.O.) from Cymbopogon citratus, C...
Optimization of Nutrient Components for Tacrolimus Production by Streptomyces tsukubaensis using Plackett-Burman followed by Response Surface Methodology
Tacrolimus belongs to macrolide lactone groups isolated from Streptomyces tsukubaensis, is used to prevent organ transplantation rejection. The aim of this study was to enhance the production of Tacrolimus by opt...
Validation Of Radiation Sterilization Dose For Proteases Immobilized On Aldehyde-Containing Textile Carriers
The main objective of this work is to establish the parameters of radiation sterilization for three proteolytic enzymes (papain, trypsin and subtilisin) immobilized on aldehyde-containing textile carriers in term...