OCCURRENCE AND ANTIBIOGRAM OF IMIPENEM RESISTANT BACTERIA IN SACHET WATER SOLD IN CALABAR METROPOLIS, NIGERIA.
Journal Title: World Journal of Pharmaceutical and Medical Research - Year 2018, Vol 4, Issue 10
Abstract
Sachet water is an affordable drinking water which is widely consumed within the Calabar metropolis. The microbial quality of this drinking water is of outmost significance to public health and can contribute to failure in the use of carbapenems for treatment of bacterial infections especially among the neonates, aged and immunocompromised individuals. This study was undertaken to investigate the occurrence and antibiotics resistance profile of bacterial isolates from the vended sachet water samples. Ten different brands of sachet water from various manufacturers were randomly collected on different occassions and transported to the laboratory for analysis within 18h using the surface plating technique for isolation of bacteria. The isolates were subjected to imipenem susceptibility testing and susceptibility to other antibiotics following Clinical Laboratory Standard Institute (CLSI, 2009) guidelines. Eleven (22%) of the isolates were imipenem resistant, 24(48%) showed intermediate resistance and 15 (30%) were susceptible to imipenem. The species composition and frequency of isolation were: Salmonella spp (9%), Pseudomonas aeruginosa (6%), Aeromonas spp (20%), Proteus spp (10%), Citrobacter freundii (17%), Plesiomonas spp (3%), Serratia spp (6%), Enterobacter spp (17%), Acinetobacter spp, (3%), Klebsiella spp (9%). All the imipenem resistant isolates showed multiple resistance to the antibiotics except Citrobacter freundii which was resistant to only one antibiotic. The number of antibiotics other species showed resistance were Enterobacter spp (10 antibiotics), Acinetobacter spp (9 antibiotics), Plesiomonas spp (8 antibiotics), Pseudomonas aeruginosa (8 antibiotics), Salmonella spp (2 antibiotics), Proteus mirabilis (5 antibiotics), Serratia spp (5 antibiotics) and Klebsiella spp (4 antibiotics). The multiple antibiotics phenotype of these isolates is a threat to an effective therapy and may contribute to increased mortality and morbidity rates as well as other outcomes. Consequently, monitoring of the water quality of these vended sachet water should be given a top priority.
Authors and Affiliations
Archibong, C. P.
Keywords
Related Articles
- EP ID EP665720
- DOI -
- Views 179
- Downloads 0
SYNERGISTIC EFFECT OF NIACIN AND COENZYME Q10 AGAINST CCL4 INDUCED LIVER FIBROSIS IN RAT MODEL
Liver fibrosis is a pathological disease resulting from chronic liver inflammation worldwide. The present study discusses the efficacy of niacin, coenzyme Q10 (CoQ10) and their combination against liver fibrosis induced...
RASA DRAVYA AND THEIR USE IN THE MANAGEMENT OF LIFE STYLE DISEASES: AN AYURVEDA PERSPECTIVE
Rasa Shastra, an integral part of Ayurveda deals with Rasa (mercury) and other minerals, metals, herbal poisonous plants and aquatic origin substances. The Rasa aushadhi so prepared offers potent immunization, has rejuve...
ASTHI VIKARAS AND ASTHI SHARIRA: A REVIEW BASED ON AYURVEDA LITERARY
Ayurveda is the most ancient practicing system of Indian medical science. The Ayurveda provides various principles related to the healthy living & body constitution. As per ayurveda the internal composition of Sharira in...
PREVALENCE OF POST PARTUM DEPRESSION AMONG THE PATIENTS REPORTING COMBINED MILITARY HOSPITAL CMH LAHORE USING EPDS SCALE
Background: To find out the prevalence of postpartum depression amongst the patients reporting combined military Hospital Lahore using Edinburg Postpartum Depression scale. Methods: This was a cross sectional, non-interv...
CONSEQUENCES OF AGING
Aging is an inevitable change for all living organisms. Most people go panic about getting old. Its not the aging but the consequences of aging which troubles them. With principles of Ayurveda, it’s possible to slow down...