Pharmaco bacteriological investigation of erythromycin, cephalexin, cephradine, amoxycillin and ciprofloxacin against different strains of klebsiella pneumonaie, escherichia coli, pseudomonas aeruginosa, staphylococcus aureus and salmonella species
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2019, Vol 5, Issue 4
Abstract
Different groups of antibiotics quinolones macrolides penicillin and cephalosporins were chosen and used in this study These antibiotics included ciprofloxacin erythromycin amoxycillin cephalexin and cephradine respectivelyTwenty six bacterial species were collected from urine milk rectal swabs liver wounds intestine and also from isolated culture which were supplied by the department of microbiology faculty of veterinary medicine university of Khartoum Sudan Identification was done by using identification kits namely Quick GN Nissui and also by using biochemical tests as confirmatory tests The bacterial species were found to be Klebsiella pneumonaie Escherichia coli Pseudomonas aeruginosa Staphylococcus aureus and six strains of Salmonella species Sensitivity tests were performed for all these organisms against various antibiotics with different concentrations using standard disk diffusion methodCiprofloxacin was found to be the most effective drug against all the organisms tested even at a very low concentration 0781 g ml all the Gramnegative bacteria were found to be resistant to erythromycin Pseudomonas aeruginosa strains were found to be highly sensitive to ciprofloxacin and resistant to the most of the other groups of antibiotics Quinolon group Ciprofloxacin ofloxacin and pefloxacin was found to be the most effective group against Salmonella typhi Keywords Erythromycin Cephalexin Cephradine Amoxycillin Ciprofloxacin E coli Klebseilla Salmonella spp
Authors and Affiliations
Abdelrahman M. A. Saeed
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