Przydatność kliniczna i diagnostyczna oznaczeń D–dimeru w różnych stanach chorobowych
Journal Title: Folia Medica Lodziensia - Year 2016, Vol 43, Issue 1
Abstract
There are many methods dedicated to assessing D–dimer. They are divided into two categories: qualitative and quantitative methods. All the methods are based on immunochemical reaction with the use of monoclonal antibodies against D–Dimer. Nevertheless, the results obtained with use of various methods are not comparable. However detection of D–dimer is used in the diagnosis of many diseases, the disease cannot be defined unambiguously without additional testing. The reason is insufficient specificity of this assay for specific diseases. Elevated D–dimer level is observed in conditions such as: pregnancy, hyperthyroidism, inflammations, tumors, and in elderly patients, but also in a life–threatening conditions like heart attack, disseminated intravascular coagulation, the rupture of the aorta or embolism. It is necessary to adhere to the principles of quality management to ensure reliable and clinically useful results of D–dimer testing.
Authors and Affiliations
Kinga Rośniak–Bąk, Marek Łobos
Keywords
Related Articles
- EP ID EP200476
- DOI -
- Views 119
- Downloads 0
Rola mesalazyny w chemoprewencji raka jelita grubego
Colorectal cancer (CRC) is the fourth most commonly diagnosed cancer in females and the third in males. Every year there are more than a million new cases of colorectal cancer and more than six hundred thousand patients...
Czy „cichy” polimorfizm pojedynczego nukleotydu (SNP) C1236T genu ABCB1 jest związany z predyspozycją do rozwoju depresji i skutecznością jej leczenia? - badanie wstępne
Introduction: According to the World Health Organization about 350 million people around the world are affected by depression. Despite the high prevalence of this disease the mechanism of depression origination as well a...
Zaburzenia procesu O-GlcNAcylacji w nowotworach
O-GlcNAcylation is a post-translational modification involving the addition of a N-acetylglucosamine moiety to the serine/threonine residues of cytosolic or nuclear proteins. Two enzymes are responsible for cyclic O-GlcN...
Ocena jakości snu w odniesieniu do stężenia serotoniny i melatoniny w surowicy u osób z marskością wątroby
Sleep disorders occur in people who suffer from liver cirrhosis, this usually involves a change in the rhythm of melatonin secretion and its metabolism. Delayed sleep phase syndrome does not always correlate with the deg...
Ocena profilu lipidowego u pacjentów aglomeracji łódzkiej leczonych statynami
Introduction: In more than the half of the population in Europe, including Poland, blood lipid profile is abnormal. These abnormalities are: high total cholesterol (TCh) levels (> 5.0 mmol/L or 190 mg/dL), often accompan...