Retinol-binding protein-4
Journal Title: Journal of Analytical Bio-Science - Year 2011, Vol 34, Issue 5
Abstract
Retinol-binding protein (RBP) is one of the members of the lipocalin family, which binds and transports retinol (vitamin A). Recent studies revealed that RBP has several isoforms; cellular RBP-1, -2 and -3, and plasma RBP-4 (also traditionally known as ''RBP''). Cellular RBPs have a role in the intercellular transport of retinoids (i.e., retinol, retinal and retinoic acid). Plasma RBP-4 is synthesized mostly in liver, but little in adipose tissue (especially, in visceral fat). Because plasma RBP-4 of liver origin is measured as a marker of nutritional status and that of adipose tissue origin as a marker of insulin resistance, we overviewed the assay methods for both plasma RBPs of liver and adipose tissue origin, together with their plasma concentrations observed by each method.
Authors and Affiliations
Hiroshi Ihara
Keywords
Related Articles
- EP ID EP103086
- DOI -
- Views 111
- Downloads 0
Preperitoneal fat thickness (PFT) of patients undergoing a medical examination assessed by an ultrasonographic method
We investigated whether the accumulation of visceral fat, assessed by a simple but widely used ultrasonographic method, was associated with a metabolic syndrome in patients undergoing a medical examination. The subjects...
[i]In vitro[/i] and [i]in vivo [/i]studies of the anti-immortalized effects of Hohrokutake ([i]daedalea dickinsii yasuda[/i]) extract on the immortalized cell line established from bovine granulosa cells
1. [i]In vitro[/i] experiment The growth of immortalized cells was found to perfectly inhibit Eagle's medium containing a small amount of the extract. 2. [i]In vivo[/i] experiment The immortalized cells were injected...
Clinical sample comparison of eight homogeneous assay kits for high density lipoprotein cholesterol and low density lipoprotein cholesterol
Homogeneous assay to measure the cholesterol associated with high- density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C) are widely used in clinical laboratories all over the world. However, few reports have be...
Development of THP assay and clinical applications
Tamm-Horsfall protein (uromodulin) is the most abundant glycoprotein in human urine. It is synthesized exclusively in the thick ascending limb of the loop of Henle. Its biological function remains unclear. Qualitative an...
Reaction between cationic detergent and Coomassie Brilliant Blue G-250: application to urinalysis
In the qualitative test for urine protein by a test strip, a false-positive reaction due to a cationic detergent is well known. A method which can discriminate a false-positive reaction was studied, using CBB G-250 reage...