Retrospective Study of Clinico- Immunological Progress of Human Immunodeficiencyvirus/Acquired Immune Deficiency Syndrome Patients on Antiretroviral Therapy at Central India
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 8
Abstract
Introduction: Human immunodeficiency virus infection (HIV) remains a worldwide health crisis. Nearly 40 million people infected, 95% of them lives in developing countries like India, Africa etc. Aim of study is to assess immunological and clinical progress of human immunodeficiency virus/acquired immune deficiency syndrome (HIV/ AIDS) patients on antiretroviral therapy (ART). Material and Methods: This was the retrospective study which was carried out in ART plus center at Gandhi medical college and Hamidia hospital Bhopal from March 2008 to March 2016. This enabled patient’s follow-up for WHO clinical stage, weight and functional status of all these patients for minimum of one year. Results: Total of 5295 HIV/AIDS patients were registered while 1903 patients were shown to take ART and were regularly follow up visit to the ART Center. Follow up status after 1 year on ART revealed that, 89.65% patients were still active and 71.4% had “good” adherence level. Median weight of the patients increased to 58 kg (improved by 12%). Change in CD4+ cell count was 104.5 (45.24%) and 199.75 cells/mm3 (86.47%) after 6 and 12 months on ART respectively. Functional status as working improved by 20.71%. Conclusion Immunological and clinical improvements as reported by increase in weight, CD4+ cell count and functional status of patients after initiation of ART.
Authors and Affiliations
Ayush Dubey, Jeetandra Sharma, Lokendra Dave, Hemant Verma, Bhavishya Rathore
Keywords
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