Study of Genitourinary malformations in perinatal autopsies
Journal Title: Indian Journal of Pathology and Oncology - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Congenital malformations remain a common cause of perinatal deaths and even though ultrasonography can give fairly accurate diagnosis, perinatal autopsy is essential to confirm the diagnosis and look for associated malformations. Aim: To emphasize the importance of perinatal autopsy in diagnosing Genitourinary malformations. Study Design: Retrospective analysis of cases with fetal genitourinary malformations was done. All fetuses were examined with external and internal examination and histopathological examination. Materials and Material: Present study comprises of 200 cases of perinatal autopsies out of which 17cases of genitourinary malformations were studied. Results: A total of 17 cases with Genitourinary malformations were studied. Most of them were renal malformations. Of all, 8 were cystic diseases of kidney, 3 cases of bilateral renal agenesis and 2 were unilateral, 1 case of urethral stenosis and 3 cases of extrophy of bladder were found. Among associated syndromes multicystic dysplasia found in Meckel gruber, Majawasky and Potters syndrome, whereas OEIS complex showed Extrophy of bladder. In Edward’s syndrome bilateral polycystic kidneys were found. Conclusion: Even though the prenatal ultrasonography reasonably predicts the malformations, fetal autopsy is essential to look for additional malformations.
Authors and Affiliations
Shailaja A. Kupati, Anita A. M, Anuradha G. Patil, Sainath K. Andola
Keywords
Related Articles
- EP ID EP312829
- DOI 10.18231/2394-6792.2017.0052
- Views 58
- Downloads 0
Diagnostic accuracy of squash cytology and role of GFAP immunoexpression in glial tumors
Introduction Intraoperative squash technique provides rapid and reliable diagnosis which is helpful to monitor or modify the treatment approach We carried out the present study to compare the accuracy of squash preparati...
Recent trends in histopathological spectrum of malignancies among females in western Maharashtra
Introduction Aim of this study is to evaluate the histopathological spectrum of female malignancies with a motive to understand the prevalent trends of this complex diseaseMaterials and Methods This was a retrospective a...
A study of patterns of anemia in hospitalized infants at a tertiary care hospital
Introduction: Anemia can negatively affect cognitive development, school performance, physical growth and immunity of the children if not treated during infancy. Objectives: To determine the pattern of anemia among 6 mon...
Spectrum of histopathological changes in fibroadenoma of breast
Introduction Fibroadenoma commonly known as Breast Mouse is freely mobile benign tumour of the breast It is composed of epithelial and stromal components These components may show varied histomorphological changes The ai...
Core needle biopsy verses fine needle aspiration cytology in palpable breast lesions- a comparative study
Background: Cytological diagnosis has its own limitations specially in suspicious lesions and poorly circumscribed lesions in Breast. Core needle biopsy (CNB) emerged as an important tool in assessment of breast lesion w...