STUDY OF SERUM MAGNESIUM LEVELS IN CRITICALLY ILL PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 42
Abstract
BACKGROUND Magnesium is the fourth most abundant cation in the body. Hypomagnesaemia is common in critically ill patients, and there is strong, consistent clinical evidence that it is associated with increased need for mechanical ventilation, prolonged ICU stay and increased mortality. There is a current need to expand our knowledge with regards to magnesium homeostasis and its impact on survival and prognosis of critically ill patients. Aims and Objectives- To study the serum total magnesium in critically ill patients and to assess the primary critical medical conditions associated with abnormalities of serum magnesium and to correlate serum magnesium levels with patient outcome in terms of length of stay and mortality. MATERIALS AND METHODS This was an observational study carried out in the medical intensive care unit at a tertiary care hospital. A total of 95 patients were included in the study during a 2-year period. Serum magnesium levels were recorded on the day of admission to intensive care unit. They were followed up to assess associated electrolyte abnormalities, the length of stay and mortality. RESULTS At admission, the incidence of hypomagnesaemia was 52.6%; 27.3% patients had hypermagnesaemia, while 20% patients had normomagnesaemia. A significantly higher APACHE II Score was recorded in subjects with hypomagnesaemia compared to those with normomagnesaemia. Hyponatraemia was seen in 76% patients, while 29.4% patients had hypocalcaemia and 44.2% had hypokalaemia. Length of ICU stay was found to be significantly higher in subjects with hypomagnesaemia compared to those with normomagnesaemia and hypermagnesaemia (p < 0.0001). Mortality was higher in patients with hypomagnesaemia (80%), while that in the hypermagnesaemia group had 53.8% mortality. CONCLUSION This study revealed the prevalence of dysmagnesaemia in the critically ill population of ICU and highlighted the role of magnesium monitoring. This study also showed that hypomagnesaemia was associated with higher APACHE II score, longer ICU stay and greater mortality.
Authors and Affiliations
Nikhil Elenjickal, Devpriya Lakra
Keywords
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- EP ID EP214127
- DOI 10.14260/Jemds/2017/722
- Views 124
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