SWIMMING EXERCISE STIMULATES NEURO-GENESIS IN THE SUBVENTRICULAR ZONE VIA INCREASE IN SYNAPSIN I AND NERVE GROWTH FACTOR LEVELS
Journal Title: Biology of Sport - Year 2014, Vol 31, Issue 4
Abstract
In this study, we investigated the effects of 8-weeks of swimming exercise on neurogenesis in the subventricular zone (SVZ) and on the levels of nerve growth factor (NGF) and synapsin I protein in the olfactory bulb (OB) of adult rats at a series of relevant time points (2 days, 1 week, 2 weeks, 4 weeks, 3 months, and 6 months). Ninety-six male Sprague Dawley rats were divided into 2 groups: (1) a control group (COG; n = 48, n = 8 for each time point) and (2) a swimming exercise group (SEG; total n = 48; n = 8 for each time point). SEG performed swimming exercise for 5 days per week over a period of 8 weeks. We found that the number of 5-bromo-2’-deoxyuridine-5’-monophosphate (BrdU)- and doublecortin (DCX)-positive cells was significantly higher in SEG than in COG at all time points (Day 2, Week 1, Week 2, Week 4, Month 3, and Month 6; p < 0.001). Furthermore, NGF and synapsin I protein levels were significantly higher in SEG on Day 2, and Weeks 1, 2, and 4 than in COG (p < 0.05 for each time point). Our findings suggest that regular swimming exercise in adult rats increases neurogenesis, neuronal survival, and neuronal maintenance in the SVZ; furthermore, swimming exercise increases the levels of NGF and synapsin I in the OB.
Authors and Affiliations
Chang-Hun Chae, Sung-Lim Jung, Sang-Hyun An, Bum-Young Park, Tae-Wan Kim, Suk-Woo Wang, Jong-Hyuck Kim, Hyo-Chul Lee, Hyun-Tae Kim
Keywords
Related Articles
- EP ID EP59217
- DOI -
- Views 139
- Downloads 0
BLOOD FLOW RESTRICTED RESISTANCE TRAINING ATTENUATES MYOSTATIN GENE EXPRESSION IN A PATIENT WITH INCLUSION BODY MYOSITIS
Inclusion body myositis is a rare idiopathic inflammatory myopathy that produces extreme muscle weakness. Blood flow restricted resistance training has been shown to improve muscle strength and muscle hypertrophy in incl...
THE ACUTE EFFECT OF WHOLE BODY VIBRATION TRAINING ON FLEXIBILITY AND EXPLOSIVE STRENGTH OF YOUNG GYMNASTS
The purpose of this study was to examine the acute effect of a single bout of whole body vibration (WBV) on flexibility and explosive strength of lower limbs in young artistic gymnasts. Thirty-two young competitive gymna...
Changes of muscle torque after sprint and endurance training performed on the cycle ergometer
The aim of this work was the specification of the influence of the sprint and endurance training performed on the cycle ergometer on changes of muscle torque. Forty three students of the Academy of Physical Education in...
Potential negative effects of chlorinated swimming pool attendance on health of swimmers and associated staff
Swimming is a recommended activity to achieve good health and to prevent certain pathologies of the circulatory, pulmonary and locomotive systems. However, recent research has focused on the possible hazard of chlorinate...
EFFECTS OF CYCLIC STATIC STRETCH ON FATIGUE RECOVERY OF TRICEPS SURAE IN FEMALE BASKETBALL PLAYERS
Static stretch is a safe and feasible method which usually is used before exercise to avoid muscle injury and to improve muscle performance. The purpose of this study was to determine the effects of cyclic static stretch...