Synovial Sarcoma of the Liver – A Case Report
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2011, Vol 4, Issue 2
Abstract
We report a case of synovial sarcoma of liver in a 44 year old man, presented as a tumor mass in left hepatic lobe. The patient was admitted at the hospital with clinical symptoms of acute abdomen and severe pain in the right upper quadrant. Imaging examinations showed a tumor mass in the left hepatic lobe and free liquid in the abdominal cavity, due to the rupture of the tumor. A resection of 2 segments of the left hepatic lobe, where the tumor was located, was performed. Morphological, immunohistochemical and FISH studies confirmed the diagnosis of monophasic synovial sarcoma. Additional clinical and imaging examinations, made after the surgery, did not confirm tumor mass in any other localization. The patient refused any therapy other than surgery, at that time. A relapsing tumor mass was found 6 months later and another surgical intervention was done. The patient received five monotherapy cycles of Doxorubicin, 75 mg/m2, after the second surgical intervention. He is still alive 11 months after the first operation receiving the same therapy and having second relapsing inoperable tumor mass filling the retroperitoneal space and a great fraction of the abdominal cavity.
Authors and Affiliations
Vesna Janevska| Institute of Pathology, Faculty of Medicine, University “Ss Cyril and Methodius”, Skopje, Republic of Macedonia, Vanja Filipovski| Institute of Pathology, Faculty of Medicine, University “Ss Cyril and Methodius”, Skopje, Republic of Macedonia, Saso Banev| Institute of Pathology, Faculty of Medicine, University “Ss Cyril and Methodius”, Skopje, Republic of Macedonia, Vlado Janevski| University Clinic of Digestive Surgery, Faculty of Medicine, University “Ss Cyril and Methodius”, Skopje, Republic of Macedonia, Alen Jovcevski| University Clinic of Digestive Surgery, Faculty of Medicine, University “Ss Cyril and Methodius”, Skopje, Republic of Macedonia, Liljana Spasevska| Institute of Pathology, Faculty of Medicine, University “Ss Cyril and Methodius”, Skopje, Republic of Macedonia, Rubens Jovanovic| Institute of Pathology, Faculty of Medicine, University “Ss Cyril and Methodius”, Skopje, Republic of Macedonia, Slavica Kostadinova-Kunovska| Institute of Pathology, Faculty of Medicine, University “Ss Cyril and Methodius”, Skopje, Republic of Macedonia, Blagica Dukova| Institute of Pathology, Faculty of Medicine, University “Ss Cyril and Methodius”, Skopje, Republic of Macedonia
Keywords
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- EP ID EP8804
- DOI 10.3889/MJMS.1857-5773.2011.0168
- Views 346
- Downloads 16
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