Synthesis of Carbethoxycinnoline Derivatives and Antimicrobial Evaluation
Journal Title: Journal of Biological and chemical Chronicles - Year 2018, Vol 4, Issue 2
Abstract
3-Carbethoxy-6-substituted-4-methylcinnolines have been synthesized by cyclization of phenylhydrazonocarbethoxyacetones under microwave irradiations using polyphosphoric acid as condensing agent. The phenylhydrazonocarbethoxyacetones are prepared from benzenediazonium chloride and ethylacetoacetate. The antibacterial potential of the title compounds has been described against different bacteria’s.
Authors and Affiliations
Komal Jakhar
Keywords
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