THE ACTIVITY OF 3-(HYDROXYIMINO)PENTAN-2,4-DIONE IN THE REACTIONS WITH RADICALS
Journal Title: Праці Наукового товариства ім. Шевченка - Year 2017, Vol 48, Issue
Abstract
The isonitrosoketon 3-(hydroxyimino)pentan-2,4-dione (HIPD) was synthesized by the nitrosation reaction of acetylacetone. The method of EPR spectroscopy confirmed the formation of a stable diacetyliminoxyl radical by oxidation of HIPD with iodobenzene diacetate PhI(OAc)2 in acetic acid. A triplet with intensities of 1: 1: 1 is observed in the EPR spectrum, due to the interaction of a spin of an unpaired electron with a spin of the nucleus of a nitrogen atom. The antiradical activity of HIPD in reaction with 2,2-diphenyl-1-picrylhydrazyl by UV / visible spectroscopy was investigated. Comparing the value of EC50 (antioxidant concentration, by which discoloration of 50% DPPH initial solution happens) for oxime and ascorbic acid standard, it has been shown that 3-(hydroxyimino)pentane-2,4-dione exhibits low antiradical activity. The inhibitory properties of 3-(hydroxyimino)pentane-2,4-dione in the processes of liquid phase initiated oxidation of isopropylbenzene and benzyl alcohol was investigated. It has been established that HIPD manifests itself in these reactions as a weak inhibitor. The rate constants of the reaction of the chain breakage with peroxy radicals of the substrates on the HIPD molecules were determined.
Authors and Affiliations
Mykhaylo KOMPANETS, Tetiana KAMENEVА, Оlha ZOSENKO, Igor KRYLOV, Olexandr SHENDRYK
Keywords
Related Articles
- EP ID EP325526
- DOI -
- Views 72
- Downloads 0
EMOTIONAL INTELLIGENCE AS RESOURCE OF STRESSRESISTANCE OF PERSONALITY
The concept of emotional intelligence is relatively new in psychology. There are different models of understanding emotional intelligence. In particular, D.Goleman includes into this term ability to self-motivation, resi...
TREATMENT OF ACUTE SENSORYNEURAL HEARING DISORDERS. HYPERBARIC OXYGENATION OR HYPOBARIC HYPOXIA?
В лікуванні сенсоневрального порушення слуху, часто пов’язаного з розладами васкуляризації внутрішнього вуха в наш час широко застосовується гіпербарична оксигенація. На підставі вивчення праць проф.В.Я.Березовського про...
THE INFLUENCE OF SURFACTANTS AND PH OF ENVIRONMENT ON THE ELECTRO-SURFACE PROPERTIES OF AQUEOUS SUSPENSION OF TITANIUM DIOXIDE
To regulate the electro-surface properties of aqueous suspensions of amphoteric oxides and their aggregative stability, changes in the pH of the medium and the addition of surfactants are often used. In this work, the ef...
Андрій Пясецький — видатний лісознавець, український патріот, громадський діяч [Andrij Pjasec'kyj — prominent scientist forester, ukrainian patriot, public activist]
The famous Ukrainian scientist in the field of forest ecology and social activist. Carpathian forests with Pinus cembra composed investigated. He developed the first natural and historic regionalization of forests of Wes...
CYTOPROTECTIVE EFFECT OF NOVEL 4-THIAZOLIDINONE DERIVATIVES AGAINST STRESS CONDITIONS IN SMALL INTESTINE OF RATS
Stress affects the integrity of the intestinal barrier and increases it permeability, reduces mucosal blood fl ow due to catecholamines driven vasoconstriction, leading to hypoxia and nitroso-oxidative processes. The exp...