The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients
Journal Title: The Medical Bulletin of Haseki - Year 2020, Vol 58, Issue 4
Abstract
Aim: To evaluate the effects of residual renal function (RRF) on anemia treatment, phosphorus control and nutritional parameters in peritoneal dialysis (PD) patients. Methods: PD patients were retrospectively analyzed. Besides anthropometric measurements, biochemical measurements, such as residual glomerular filtration rate (rGFR), normalized protein catabolic rate (nPCR), hemoglobin (Hb), serum albumin, calcium, phosphorus, ferritin, parathormone and C-reactive protein levels were recorded. Results: One hundred and fifteen patients (52 females, 63 males; mean age: 56.0±13.2 years 20-83 years) receiving PD treatment were analyzed. The patients were divided into two groups according to presence or absence of RRF (n=75 and n=40, respectively). Patients with RRF had higher body weight (80±14 kg vs 68±13 kg; p<0.001), body mass index (29±5 kg/m² vs 25±5 kg/m²; p=0.009) and serum albumin level (3.6±0.5 vs 3.4±0.5 g/dL; p=0.027]. Patients with RRF had lower erythropoietin [29 (39%), vs. 34 (85%); p<0.001), sevelamer [17 (22.7%) vs 24 (60%); p<0.001] and calcimimetic [9 (12%) vs 14 (35%); p=0.007] usage rates and lower ferritin [159 (88-259) ng/mL vs 323 (170-495) ng/mL; p=0.001] level. rGFR was found to be positively correlated with Hb (r=0.274; p=0.017) and nPCR in patients with RRF (r=0.251; p=0.030). Conclusion: In our study, the positive effects of RRF on the treatment of anemia, phosphorus control and nutritional status in PD patients were shown.
Authors and Affiliations
İbrahim Halil Düşünceli, Metin Ergül, Necmi Eren, Betül Gönüllü Kalender, Erkan Dervişoğlu
Keywords
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- EP ID EP688703
- DOI 10.4274/haseki.galenos.2020.6091
- Views 146
- Downloads 0
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