THE EFFECT OF SUPERDISINTEGRANTS ON THE DISSOLUTION OF CALCIUM CARBONATE FAST DISSOLVING TABLETS
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 3
Abstract
The objective of the present study is to design and evaluate the effect of disintegrating agents such as Starch, Cross Caramellose Sodium, Sodium starch glycolate and crosprovidone Calcium carbonate conventional tablets simultaneously. The nature of calcium carbonate which forms cake on standing which affects the drug disintegration process there by inhibits the drug release from the Conventional Tablet. Hence in the present study the effect of disintegrating agents at different concentrations is carried out on both the drugs simultaneously and finding out the best concentration followed by stability studies for a period of 3 months.
Authors and Affiliations
Mohammed Farhana, J. Preeti, Md Faizulla, Budda Chellibabu, Harish. G, Rajnish Kumar Singh
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