The influence of antiparasitic medicinal product closaverm-A on some biochemical blood indices of cows suffering from mixed invasion
Journal Title: Біологія тварин - Year 2014, Vol 16, Issue 3
Abstract
The aim of work was to study the influence of medicinal product Closaverm-A on some biochemical blood indices suffering from mixed invasion. The cows with body weight 450–550 kg were used in the test. Before administration of medicinal product the cows were examined by means of scatoscopy method of consecutive flushings for the presence of fasciola eggs and Fulleborn’s method for the presence of eggs of intestinal nematodes. The intensiveness of invasion was detected by means of Trach’s method. The control group contained animals without helminth eggs, cows suffering from mixed invasion were divided into two experimental groups. The cows from one experimental group were administered antiparasitic medicinal product Closaverm-A intramuscularly in the dose of 0.5 ml on 10 kg of body weight. On the 14th and 21st day after administration of medicinal product the blood was collected from jugular vein and the biochemical test were conducted due to generally accepted methods for studying of the influence of Closaverm-A on the organism. On the 14th and 21st day after administration of medicinal product Closaverm-A the signs of activity strengthening of asparagine aminotransferase on the background of low activity of alkaline phosphatase were detected. Such changes in activity of abovementioned blood enzymes could be associated with disorders of heart and liver activity on the background of intoxication caused by helminthes and the influence of anrtiparasitic medicinal product. The cows treated with Closaverm-A showed disappearance of helminthes and improvement of metabolism in comparison with untreated animals that showed increase of β-, γ- and α2-globulin number that indicated function disorder of liver associated with invasion.
Authors and Affiliations
O. L. Tishyn, K. O. Vysotska-Kalyniuk
Keywords
Related Articles
- EP ID EP366144
- DOI -
- Views 100
- Downloads 0
The influence of phospholipid-containing preparations on the level of immunoglobulin M in the serum of blood of calves during the period of formation of colostral immunity
The results of application of preparation “Membranostabil” and phospholipid-bilayer macrocapsules on the base of soy-bean lecithin developed by us with the aim of correction of indexes of content of immunoglobulin M in t...
Specificity of cell-envelop proteinase of lactococci toward the casein fractions
The specificity of cell-envelop proteinases of lactococci toward the casein fractions plays an important role in formation the parameters of quality of fermented dairy products, as well as in the creation of natural orig...
Physical and chemical composition of goat and sheep milk depending on the altitude of grazing
The indicators of quality and safety of sheep and goat milk were compared depending on the altitude of grazing in the valleys of Zakarpattya (251, 309, 341, 376, 394, 524, 580 and 750m above sea level). The milk samples...
Development of vitamin-hormonal phytopreparations for prevention of perinatal pathologies in sheep and goats
The successful conduct of the livestock industry is connected with the importance of regulation and correction of reproductive function in animals, which results in search of modern, safe and practical methods of hormone...
Glutathione-related enzymes of liver and caecum of animals
The activities of glutathione S-transferase, glutathione peroxidase and glutathione reductase and the concentration of glutathione in liver and mucosa of caecum of cattle, guinea pig, horse, pig, rabbit and sheep have be...