The progress in the therapy of chronic myeloid leukemia
Journal Title: Postępy Nauk Medycznych - Year 2011, Vol 24, Issue 6
Abstract
The review describes current standards of chronic myeloid leukemia (CML) treatment. Recommendation of European LeukemiaNET for CML treatment are presented. In most patients as a first line treatment in newly diagnosed CML , imatinib since several years is the treatment of choice. Recommendation of second line treatment in case treatment failure are presented. In These cases second generation of tyrosine kinase inhibitors – dasatinib and nilotinib are the most preferred drugs. Indications for allogenic bone marrow transplantation for the resistant patients are also presented. Besides, new trends – which are at the stage of clinical trials aimed to cure the disease are presented.
Authors and Affiliations
Witold Prejzner, Andrzej Hellmann
Keywords
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