The Quality Of Life of Patients as a Criterion of Efficacy of Primary Open Angle Glaucoma Therapy
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 5
Abstract
a shift of QOL score in patients is one of the most important of therapy efficacy indicators for treatment of ophthalmic diseases, such as primary open angle glaucoma (POAG). The main goal of treatment of patients with POAG is to stabilize the ocular pressure and to stop progression of the disease. The purpose of the study was to identify changes in QOL of patients with POAG in the progress of treatment using different medicines of S01E group – ‘Antiglaucoma medicines and miotics’ (AGM). Our study involved 247 patients with POAG, whose average age was 70.27 ± 8.97 years. These patients were questioned using a standardized ophthalmic glaucoma-specific QOL questionnaire developed by us, aimed at the study of symptoms` severity, as well as their impact on various spheres of patients` activity. This method provided an opportunity not only to analyze the nature of impact of the disease on the patients` performance, but also presented a criterion for evaluating the efficacy of mono- and combined therapies, as well as revealed the feasibility of administration of AGM. It was found, that the most effective monotherapy was Lanotan, while Azopt was the lowest one. Combinations of AGM presented intermediate efficacy indicators in studied patients.
Authors and Affiliations
Kryvoviaz O. V
Keywords
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- EP ID EP386362
- DOI 10.9790/3008-1105031214
- Views 74
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