The Role of MicroRNAs in Parasitology
Journal Title: Turkish Journal of Parasitology - Year 2020, Vol 44, Issue 2
Abstract
MicroRNAs (miRNAs), as epigenetic regulators, are small non-coding RNAs regulating gene expression in eukaryotes at the posttranscriptional level to control biological functions. MicroRNAs play a role in development, physiology, infection, immunity and the complex life cycles of parasites. Also, parasite infection can alter host miRNA expression that might result in either parasite clearance or infection. Over the past 20 years, thousands of miRNAs have been identified in the nematode Caenorhabditis elegans and other parasites. Thus, miRNA pathways are potential targets for the diagnostic and therapeutic control of parasitic diseases. Here, we review the current status and potential functions of miRNAs related to protozoans, helminths, and arthropods.
Authors and Affiliations
Özlem Ulusan Bağcı, Ayşe Caner
Keywords
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- EP ID EP685224
- DOI 10.4274/tpd.galenos.2020.6776
- Views 151
- Downloads 0
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