The therapeutic targets and clinical translational research in vitiligo

Journal Title: Biomedical Transformation - Year 2024, Vol 5, Issue 2

Abstract

Vitiligo is a chronic autoimmune disease characterized by depigmentation of the skin, significantly impacting patients' quality of life. Recent advances in immunological and molecular biological studies have identified numerous potential therapeutic targets for vitiligo, paving the way for novel treatment strategies. This article reviews the advancements in researching novel immunotherapy targets such as the JAK/ STAT pathway, PDE-4, Wnt/β-catenin pathway, and IL-15, along with their respective targeted drugs. The article aims to provide insights into the clinical translation of future therapeutic targets for vitiligo.

Authors and Affiliations

Zhao Liuqi, Zou Jing, Shen Qingqing, Tong Linhui, Yang Qing, Zhang Yuehuang, Wang Honglin

Keywords

Related Articles

Placental development and preeclampsia

Serving as the interface between the fetal and maternal environment during gestation, the placenta plays critical roles in the protection of the developing fetus and the maintenance of pregnancy. The placenta is responsi...

Progress and applications of epidemiological research on myopia prevention and control for children and adolescents in the context of interdisciplinary research

Myopia has become a major global public health concern, with its prevalence increasing significantly among children and adolescents. Epidemiological research has played a crucial role in myopia prevention and control, bu...

Research progress of cell therapy in the preservation and functional repair of donor livers

Liver transplantation is the most effective treatment for end-stage liver diseases. However, the shortage of donor livers severely restricts the application of liver transplantation, and the impairments of liver function...

Influence of cardiovascular health behaviors and factors on the incidence of hypertension in young and middle-aged population

Objective Aims to investigate the effects of these ideal cardiovascular health behaviors and factors on the incidence of hypertension in young and middle-aged populations. Methods A cohort of 5 372 employed individuals w...

Research progresses in delaying aging by targeting DNA damage repair

Genomic instability is the primary hallmark of aging. Since DNA damage is one of the core aspects contributing to genomic instability, it has been long recognized as a critical cause of aging. Here, we summarized the int...

Download PDF file
  • EP ID EP766008
  • DOI 10.12287/j.issn.2096-8965.20240213
  • Views 15
  • Downloads 0

How To Cite

Zhao Liuqi, Zou Jing, Shen Qingqing, Tong Linhui, Yang Qing, Zhang Yuehuang, Wang Honglin (2024). The therapeutic targets and clinical translational research in vitiligo. Biomedical Transformation, 5(2), -. https://www.europub.co.uk/articles/-A-766008