To study left ventricular structural abnormalities in patients of diabetes mellitus with chronic kidney disease
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2017, Vol 3, Issue 11
Abstract
Background: Macro vascular as well as micro vascular complications are the predominant cause of mortality in Diabetes Mellitus. Cardiovascular complications of diabetics largely account for the morbidity and mortality among diabetic patients. The most common cardiovascular complication of diabetics in ESRD is left ventricular (LVH) hypertrophy and it is also an independent risk factor for survival. These patients have higher proportions of abnormal LV geometry, with LV concentric remodeling and LV concentric hypertrophy as the most frequent pattern. The current study attempted to study prevalence and pattern of left ventricular hypertrophy in diabetic patients with chronic kidney disease. Methods: Data was examined from sixty patients of 20-60 years after thoroughly examining and applying exclusion criteria. These sixty patients divided into two groups of thirty each: Group I consisted of DM with CKD stage 3-4 (GFR > 15) Group II consisted of DM with CKD stage 5 (GFR ≤ 15) Echocardiography was done in all the cases. Measurements of interventricular septal wall thickness (IVSD), LV end diastolic dimension (LVEDD) and posterior wall thickness in diastole (PWTD) were recorded in accordance with the American Society of Echocardiography recommendations using M-mode. Left ventricular mass index was calculated. Left ventricular mass index (LVMI) was used to characterize LV geometry. Result: The prevalence of various left ventricular geometry according to GFR in present study were as –in diabetic patients in Group I, the proportion of patients having concentric hypertrophy was 10%, concentric remodeling 13.3%, eccentric hypertrophy 16.7%. in Group II , the prevalence of patient having concentric hypertrophy was 43.3%, concentric remodeling 23.3%, eccentric hypertrophy 10 %. There was significant difference in proportions of various LV geometry between two groups (p = 0.006; significant). Conclusion: This depicted that patients with severe CKD had high proportions of various LV geometry as compared to patients with moderate CKD.
Authors and Affiliations
*Rakesh Chander, **Shiv Charan,***Akanksha,***Rupinder, ***Rajvir Singh, **** N. S. Neki
Keywords
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- EP ID EP570766
- DOI 10.22192/ijcrms.2017.03.11.012
- Views 155
- Downloads 0
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