Total phenols, total flavonoids content; antioxidant and antifungal activities of ethanolic and aqueous extracts of Eleutherine bulbosa (Iridaceae)
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 12
Abstract
Ethanolic and aqueous extract of the bulb of Eleuterine bulbosa have been analyzed for their content in total phenols, total flavonoids; antioxidant and antifungal activities. The average value of total phenols was 27.12 ± 0.62 and 9.36 ± 0.55 mg. Eq.G.A /g d.M for ethanolic and aqueous extract respectively and the one of total flavonoids, 17.97 ± 0.07 and 6.15 ± 015 mg. Eq.Rt /g.d.M. In vitro antioxidant activity by DPPH method revealed the I C50 of 0.595 ± 0.004 and 1.251 ± 0.083 mg/ml respectively for ethanolic and aqueous extract, against 0.123 ± 0.005 mg/ml for Rutin (control). Antifungal activity carried out by diffusion in solid medium method showed the inhibition of Candida albicans growth by the two extracts. The IMC was 3.75 for ethanolic extract and 7.5 mg/ml for aqueous extract. The FMC was 30 mg/ml for ethanolic. These results may explain the abundant uses of this plant as a nutritional and medicinal plant.
Authors and Affiliations
Dr. . MORABANDZA CJ
Keywords
Related Articles
- EP ID EP204731
- DOI -
- Views 85
- Downloads 0
Evaluation of analgesic activity of methanol extract from the Spondias pinnata
This Present study was surpassed to investigate the methanolic fruit extracts of Spondias pinnata for analgesic activities in rats using Acetic acid induced writhing test & Formalin induced licking test. S. pinnata is a...
Comparing gangion cell complex and retinal nerve fibre layer for the early diagnosis of glaucoma
Context: With the newertechnologies like Optical Coherence Tomography(OCT), it’s time to rethink whether Retinal Nerve Fibre Layer (RNFL) thickness is the earliest tool for glaucoma detection or Ganglion Cell Complex (GC...
Synthesis of Mannich bases of pyrazolines derivatized with 1,3,4-oxadiazoles as antimicrobial agents
Mannich bases 3a-h using the morpholine and 5-methyl-4-(5-aryl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-1,3,4-oxadiazol-2(3H)-ones 2a-h were prepared. The structures of the title compounds have been characterized by IR, 1H NM...
Human taste testing and evaluation of the physicochemical properties of fine granules of sodium cromoglycate in commercial drug products
The purposes of this research were to assess palatability based on human taste testing and to evaluate physicochemical properties of sodium cromoglycate fine granules [a brand-name (CGNa-A) and two generics (CGNa-B and C...
A study to assess the oral health status and treatment needs of fishermen population in coastal region of Andhra
The study was conducted in Vodarevu coastal village of Prakasam district of Andhra was selected by multistage sampling method. All the available 158 fishermen were examined with their consent. The oral health status was...