ULTRASTRUCTURAL ORGANIZATION OF THE AORTIC WALL IN THE WHITE RAT
Journal Title: Science Review - Year 2018, Vol 3, Issue 2
Abstract
The article is devoted to the comparative study of the ultramicroscopic structure of the aortic wall in the white rat in norm. The obtained results of the study may be useful in modeling of aortic diseases, since it is necessary to take into account the peculiarities of ultrastructural organization of the aorta of the experimental animal to extrapolate the experimental data to medical practice. Using the method of electron microscopy, it was established that the aortic wall is composed of three tissue layers - the inner, represented by the endothelial cells, the sub-endothelial layer and the internal elastic membrane; medial, which consists of the external elastic membrane/lamina; and the external (outer) layer - adventitia. The latter is formed by the loose fibrous connective tissue with a small amount of collagen fibers, muscle cells and macrophages. Haemomicrocirculatory pathway vessels (HPV) start from the blood vessels located in the adventitia, penetrate the outer third of the medial layer and branch out between the outer and medial layers of the aortic wall. Despite availability of the numerous comparative studies devoted to the the anatomy of the aorta of the white rats and humans observed on the electro-microscopic level in norm, the results of our study will help to systematize and supplement the existing scientific information for further investigations of both morphologists and clinicians on the microanatomy of the aorta in terms of the development of new methods in the future diagnostics, prophylaxis and treatment of vascular pathologies. The present abstract is a part of the research work of the Lviv National Medical University named after Danylo Halytsky on "Morphological peculiarities of the haemomicrocirculatory pathway of the aortic wall of the rat in norm and in experimental diabetes mellitus".
Authors and Affiliations
M. N. Tsitovskyi, Y. Y. Kryvko, L. R. Mateshuk-Vatseba
Keywords
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