A BRIEF INTRODUCTION TO METHODS OF PREPARATION, APPLICATIONS AND CHARACTERIZATION OF NANOEMULSION DRUG DELIVERY SYSTEMS
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
Nanoemulsions have attracted great attention in delivery of therapeutically active agents since approximately 40% of new chemical entities are hydrophobic in nature and the delivery of these poorly water soluble drugs is a challenge for delivery of drugs. The emulsions and Nanoemulsions differ mainly in the size and shape of the particles dispersed in the continuous phase. The particle size in nanoemulsions is (10-200nm) and those of conventional emulsions are (1-20µm). Nanoemulsions are prepared by high energy emulsification methods like micro fluidic and ultrasonic methods, these methods rupture large micro droplets into nano scale droplets. Oil in water (O/W) and water in oil (W/O) nanoemulsions were prepared by aqueous phase titration method. Nano emulsions can be evaluated for their morphology, droplet size, viscosity, PH, optical clarity, zeta potential, conductivity, transmission electron microscopy and polydispersity. Nanoemulsions find application in controlled drug delivery, targeted drug delivery, nutraceuticals, food products, transdermal and colloidal drug delivery. This article includes preparation, characterization, evaluation and application of nanoemulsions.
Authors and Affiliations
Haritha, Syed Peer Basha, Koteswara Rao P, Chakravarthi Vedantham
Keywords
Related Articles
- EP ID EP33029
- DOI -
- Views 420
- Downloads 0
Protective effect of aqueous extract of Curcuma longa on ethanol induced Hepatotoxicity in Rat
In ethno medicinal practices, the traditional healers use the genus Curcuma for the treatment of various ailments Turmeric is a spice derived from the rhizomes of Curcuma longa, which is a member of the ginger family (...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ESTIMATION METHOD FOR SOTALOL HYDROCHLORIDE TABLETS BY USING RP-HPLC
The present investigation describes about a simple, economic, selective, accurate, precise Reverse phase High performance liquid chromatographic method for the estimation of Sotalol Hydrochloride in pharmaceutical dosa...
SYNTHESIS AND CHARACTERIZATION OF 1, 3, 4-OXADIAZOLE AND 1,3,4- THIADIAZOLE
There are vast numbers of pharmacologically active heterocyclic compounds in regular clinical use. The presence of heterocyclic structures in diverse types of compounds is strongly indicative of the profound effects su...
Classifications, properties and wide applications of nanomaterials
Nanotechnology has been developed for many years which it was not a new topic in science and was not a new technology. It is a part of science which has been developed a tremendous application for the remediation of en...
Role of Presynaptic receptors in health and disease
Maintenance of homeostasis is the norm of nature. In order to maintain homeostasis in neuronal transmission, fine tuning of neurotransmitter release from the presynaptic nerve terminals is required. This role is played...