Clinico-pathological study of breast lesions
Journal Title: Medpulse International Journal of Pathology - Year 2019, Vol 10, Issue 2
Abstract
Background: Breast lump is the most common presentation in breast diseases. It is sometimes difficult to determine whether a suspicious lump is benign or malignant simply from clinical assessment. By single method it is not always possible to diagnose a solid, cystic or benign lesions from malignant lesions. The initial provisional diagnosis must be confirmed by histopathology. Histopathological diagnosis is universally accepted confirmatory mode of diagnosis and follow up.8 Evidence from clinical follow up studies, show that there is a relationship between the presence of histopathologically proven benign breast disease and breast cancer and that the level of risk varies according to histological category of benign breast diseases. Aims and objectives: To study the spectrum of breast diseases by their mode of clinical presentation and histopathology. Materials and methods: In the 235 patients with clinically diagnosed breast lesions of both sexes attending surgery Out Patient Department in tertiary health care and undergoing further surgery were enrolled in the study. All the lumpectomy and MRM specimens received from these patients for histopathology examination were selected. A predesigned proforma was used to collect information of patients which includes general information, presenting complaints, past history if any, family history, local and systemic examination. Information of patients with clinically diagnosed breast lesions was collected. Hisopathological examination was performed in all the specimen collected. Results: In the present study 235 cases were studied clinically and histopathologically. It was observed that there were 190 cases (80.85%) of benign lesions, 35(14.89%) cases of malignant tumours and 10(4.26%) cases of inflammatory lesions. It was seen that benign breast lesions form the bulk of the breast lesions and the most common benign lesions was Fibroadenoma with 153(65.11%) cases followed by Fibrocystic diseases accounting 12 (5.10%) cases. In malignant tumours, Invasive ductal carcinoma accounting 21(8.94%) cases with highest occurrence followed by Invasive lobular carcinoma 7(2.98%) cases. There were 3 cases (1.26%) of Mucinous carcinoma, 2 cases (0.85%) of Medullary carcinoma and 1 case (0.43%) each of Papillary carcinoma, Mixed carcinoma. Chronic Mastitis (1.70%) was the most common inflammatory lesion. Acute Mastitis and Granulomatous Mastitis was diagnosed in 0.85% cases each. Conclusion: Benign lesions of the breast were more common than inflammatory and malignant lesions of the breast. The clinical diagnosis of the lump must be correlated with histopathological examination for the accurate treatment of the patient.
Authors and Affiliations
Kacharu Tukaram Dalve, Manjiri Shewale
Keywords
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- EP ID EP591114
- DOI 10.26611/1051024
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