Effect on Quality of Life of a Lentinus edodes mycelia-enriched diet (L･E･M®) in patients with terminal cancer
Journal Title: Journal of Analytical Bio-Science - Year 2013, Vol 36, Issue 2
Abstract
Purpose: It is important to offer the highest possible quality of life (QOL) for terminal cancer patients in palliative medicine. It was examined whether Lentinus edodes mycelia (L･E･M®) -containing diet (CORELEM®) was effective in improving the QOL for terminal cancer patients. Methods: Efficiency for QOL of L･E･M® was examined by repeated oral administration in a dosage equivalent to 1,000-1,500 mg L･E･M®/day to 105 terminal cancer patients for 4 weeks with placebo as a control using the double-blind parallel-group comparison test. Results: The CORELEM® group showed a significant improvement in clinical conditions of pain, depression, insomnia, and mouth dryness compared to the placebo group. Moreover, both groups showed no serious adverse events during diet ingestion. Conclusion: It was suggested that CORELEM® is effective in improving QOL and safely ingestible for terminal cancer patients.
Authors and Affiliations
Takashi Higashiguchi
Keywords
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