Enzyme-Based Bioremediation and Its Clinical Overlap: Potential Risks of Aspergillus-Derived Biocatalysts
Journal Title: Falcons Journal of Advanced Research - Year 2025, Vol 1, Issue 2
Abstract
The rise in industrial and environmental applications of microbial enzymes has brought renewed attention to the dual potential and peril posed by fungal species like Aspergillus niger. This study investigates the bioremediation efficacy of lipase enzymes derived from A. niger and critically examines the clinical overlap and associated risks of utilizing such fungal biocatalysts. While A. niger lipases have demonstrated significant potential in degrading fats, oils, and synthetic pollutants, their pathogenicity in immunocompromised individuals and presence in food chains have raised safety concerns. Utilizing recent literature, this paper explores how lipase production can be optimized under controlled fermentation, how the enzymes function in waste degradation, and how fungal remnants or spores may pose biohazards during industrial use. The findings reveal that while A. niger lipases offer high catalytic efficiency, their deployment without rigorous purification or containment measures may lead to unintended consequences, including allergenic responses or opportunistic infections. Several risk assessments, including those by EFSA and FSANZ, underscore the importance of evaluating genetically modified strains of A. niger for safe industrial use. This research contributes to the growing discourse on microbial biotechnology by emphasizing the need for biosafety protocols, genetic screening of production strains, and public health oversight. The paper concludes that the beneficial applications of A. niger lipases must be balanced with stringent regulatory frameworks to mitigate clinical risks, particularly in settings involving open bioremediation or food production.
Authors and Affiliations
Fakhira Bashir, Mawra Kokab, Saba Akhtar, Qasim Raza
Keywords
Related Articles
- EP ID EP765586
- DOI 10.63287/611139
- Views 19
- Downloads 1
Perseverance of Quality in Digital Transformation of Education during Covid-19, in Private Higher Education Institutions in Bahawalpur Region: Issues and Solutions
Due to the fact that digital transformation in the field of education has become a vital means of survival in a new and transformed world as a result of Covid-19, all public and private sector institutions in Pakistan ha...
Postcolonial Existentialism: Identity, Race, and Belonging in Contemporary South Asian Fiction
This paper explores the nexus of postcolonial existentialism and the contemporary South Asian fiction to identify identity, race, and belonging as the central concerns of the post truth and the globalized world. Utilizin...
Grassroots Movements and Policy Advocacy: A Dual Approach to Climate Activism and Social Justice
This paper explores the intersection of climate activism and social justice, with a particular focus on grassroots movements and policy advocacy. It argues that these two elements, when combined, can effectively address...
Pathogenic and Industrial Implications of Lipase Enzyme Extracted from Aspergillus niger: A Comparative Study of Biotechnological Applications and Clinical Risks
Aspergillus niger is a widely distributed filamentous fungus known for its significant role in industrial biotechnology and its potential as an opportunistic pathogen. This study investigated the production, characteriza...
The Evolution of Leadership Styles in the Era of Hybrid Work Models
The emergence of hybrid work models has redefined workplace dynamics, requiring leaders to adapt their traditional approaches to effectively manage dispersed teams. This research examines the evolution of leadership styl...