Gut microbial metabolite functional screening platform
Journal Title: Biomedical Transformation - Year 2022, Vol 3, Issue 1
Abstract
Human gut microbial metabolites are closely related to the physiological functions of the human body, and the exploration of the functions of these small molecules is an ongoing topic for researchers. With the development of metagenomics and metabolomics, and the continuous establishment and improvement of in vivo, in vitro and ex vivo models, there are more and more platforms for small molecule functional screening. This paper mainly introduces some commonly used GMM functional screening platforms, and looks forward to new technologies that may be applied in this field in the near future.
Authors and Affiliations
Li Zhunduo, Sun Hui
Keywords
Related Articles
- EP ID EP766773
- DOI 10.12287/j.issn.2096-8965.20220108
- Views 11
- Downloads 0
Translational research on Autism: An integrated pathway from mechanisms to precision diagnosis and treatment
Autism spectrum disorder (ASD), characterized by complex etiology and high heterogeneity, represents a major challenge for the global medical and scientific communities in its mechanistic elucidation and development of i...
The role of DNA double-strand break repair defects in the pathogenesis of neurodegenerative diseases
DNA double-strand break repair (DSBR) plays an important role in maintaining genome stability and cell survival. DSBR are predominately accomplished by two pathways: Homologous Recombination (HR) and Non-homologous End J...
Insights into antigen specific CD8+ T cell exhaustion
CD8+ T cells are the primary mediators of antigen-specific immune responses, with their functional states finely regulated by molecular mechanisms, playing a crucial role in tumor immunity. In recent years, CD8+ T-cell-b...
Clinical efficacy observation of yinqiao qingre tablet
Objective To evaluate the efficacy and safety of yinqiao qingre tablet in treating common cold with wind-heat type.Methods The randomized, double-blind, placebo, parallel control research were applied to this study. The...
Research progress in structural modification of Camptothecins
Camptothecin and its derivatives are alkaloids with broad-spectrum anti-tumor activities and have significant inhibitory effect on malignant tumors. Its derivatives such as irinotecan and topotecan have been on market ov...