Reexamination, analysis and correction of 1 288 cases with decreased platelet count
Journal Title: Journal of Air Force Medical University - Year 2023, Vol 44, Issue 3
Abstract
Objective To classify and identify the false-positive cases of decreased platelet (PLT) count in laboratory by means of blood smear review, and to explore relevant technical adjustment and correction, so as to provide more accurate test results for patients. Methods The routine blood samples from Tangdu Hospital from January to December 2021 were selected for analysis. The samples with PLT < 80 × 109 / L and 80 × 109 / L≤ PLT < 100 × 109 / L combined with instrument indicating PLT agglutination were reexamined by blood smear, and the morphology and distribution of PLT were observed under microscope. A total of 190 samples with false decreased PLT count were analyzed by PLT-I, PLT-F and nonanticoagulant tube. Results Among the routine blood samples from January to December 2021, 1 288 routine blood samples were reexamined by blood smear, among which 1 098 cases had decreased PLT authenticity, accounting for 85. 25% . PLT aggregation was observed in 72 cases (2 cases were improperly collected, 70 cases were confirmed to be anticoagulant dependent pseudothrombocytopenia, including 1 case of PLT satellite phenomenon), accounting for 5. 59% . Large PLT was found in 118 cases, accounting for 9. 16% . The comparison and treatment results of various types of specimens with decreased PLT count were consistent with the results of manual microscopic examination. Conclusion The false reduction of PLT count detected by blood cell analyzer is affected by many factors. The rules of laboratory reexamination should be strictly implemented, appropriate techniques and methods should be adopted to deal with and correct, and continuous improvement should be made to ensure the accuracy of the test results.
Authors and Affiliations
ZHAI Hongye, YUAN Hui, LIU Qian, GUO Wei, YANG Xiaofei, WANG Jieyu, HUANG Jing, ZHANG Lijun
Keywords
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