Urban particulate matter related ocular surface diseases and their potential pathogenic mechanism
Journal Title: Eye Science (Yanke Xuebao) - Year 2024, Vol 39, Issue 12
Abstract
More and more evidence indicate that air pollution can seriously damage human health and become a major cause of the global disease burden. The main component of air pollution, particulate matter, can penetrate the lungs and cardiovascular system, causing ischemic heart disease, pneumonia, chronic obstructive pulmonary disease, and even lung cancer, leading to an increase in the incidence and mortality rates related to air pollution. Urban particulate matter, as the main air pollution problem faced by urban residents, has been shown to be closely related to various inflammatory eye diseases, such as allergic conjunctivitis, keratitis, and dry eye. Our research further confirms that exposure to high concentration of urban particulate matter can also cause pathological structural changes and functional abnormalities in the meibomian gland, leading to inflammatory meibomian gland dysfunction. This review comprehensively summarizes the latest research on the eye surface diseases related to urban particulate matter and their pathogenic mechanisms, aims to elucidate the damage of air pollution to eye surface tissues, identify potential therapeutic targets, and guide the diagnosis and treatment of environmentally related eye diseases in clinical practice.
Authors and Affiliations
Mengqian TU, Ren LIU, Jiaxu HAN, Jianwen XUE, Lingyi LIANG
Keywords
Related Articles
- EP ID EP761501
- DOI 10.12419/24071501
- Views 25
- Downloads 0
Circuit cooperation of endoscopic trans-ethmosphenoid optic canal decompression
[Objective:] To summarize the experience of circuit cooperation in endoscopic trans-ethmosphenoid optic canal decompression (ETOCD). [Methods:] In this study, 23 patients with traumatic optic neuropathy (TON) undergoing...
Inhibitory effects of bilberry extract on oxidative damage and angiogenesis in RPE cells
[Objective:] To investigate the inhibitory effects of bilberry extract on oxidative damage and angiogenesis in retinal pigment epithelial (RPE) cells. [Methods:] Human RPE cells (ARPE-19) were divided into control, model...
Research progress in epiretinal macrophage-like cells characterized by en face OCT in ocular fundus diseases
Macrophage-like cells (MLC) refer to immune cells that originate from and function similarly to macrophages, including microglia, hyalocytes, and macrophages themselves. By setting the display level of en face OCT to the...
Effects of non-depolarizing muscle relaxants on intraocular pressure of glaucoma patients with elevated intraocular pressure during induction of general anesthesia
[Objective:] To compare the effects of different types of non-depolarizing muscle relaxants including rocuronium, cis-atracurium and mivacurium on intraocular pressure of glaucoma patients with elevated intraocular press...
Wearable device in monitoring children's quantitative visual behavior and quantitative analysis of risks related to myopia
[Objective:] To investigate a non-invasive, smart device capable of monitoring the quantitative visual behavior of school-age children, and to analyze quantitatively the relationship between visual behavior and the occur...